Delta
G
New therapies from understanding ageing
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Reading
matter <Archive>
This is just a small selection
of articles on topics related to Delta G's programmes. This is not meant to
be exhaustive: it is just an entrée to the literature.
As Delta G publishes our
own scientific papers, we will also put abstracts and, where possible, PDFs
here.
Click on the Pubmed logo
to link to the Pubmed
entry for each paper.
Hypoxia and Cancer
- Bianchi NO, Bianchi
MS, Richard SM. (2001) Mitochondrial genome instability in human cancers.
Mutation Research 488: 9-23
- Bush, RS, Jenkin, RDT,
Allt, WEC, Beale, FA, Bean, H, Dembo, AJ, Pringle, JF. (1978) Definitive
evidence for hypoxic cells influencing cure in cancer therapy. Br. J.
Cancer 37 (Suppl 3) 302 - 306
- Dewhirst MW, Secomb TW,
Ong ET, Hsu R, Gross JF. (1994) Determination of local oxygen consumption
rates in tumors. Cancer Res. 54(13):3333-6.
- Garber K. (2005) New
drugs target hypoxia response in tumours. J. Natl. Cancer Inst. 97 (17):1
- Gatenby, RA, Kessler,
HB, Rosenblum, JS, Coia, LR, Moldofsky, PJ, Hartz, WH, Broder, GJ. Oxygen
distribution in squamous cell carcinoma metastases and its relationship to
outcome of radiation therapy. (1988) Int. J. Radiation Oncol. Biol. Phys.
14: 831 - 838
- Muller-Hocker J. Mitochondria
and ageing. Brain Pathol. (1992) Apr;2(2):149-58.
- Riddick, DS, Lee, C.,
Ramji, S., Chinje, EC., Cowen, RL., Williams, KJ, Patterson, AV, Stratford,
IJ, Morrow, CS, Townsend, AJ, Jounaidi, Y, Chen, CS, Su, T, Lu, H, Schwartz,
PS, Waxman, DJ. (2005) Cancer chemotherapy and drug metabolism. Drug
Metab. Dispos. 33 (8): 1083 - 1096
- Warburg O. (1930). The
metabolism of tumors. Arnold Constable Ltd, London.
Aubrey de Grey's work
- AD de Grey (1997) A
proposed refinement of the mitochondrial free radical theory of aging.
Bioessays. 19(2):161-6.
- AD de Grey (1998) A
mechanism proposed to explain the rise in oxidative stress during aging.
J Anti-Aging Med. 1(1):53-66.
- Aubrey D.N.J. de Grey,
John W. Baynes, David Berd, Christopher B. Heward, Graham Pawelec, Gregory
Stock (2002) Is human aging still mysterious enough to be left only to
scientists? BioEssays 24 (7): 667 - 676
- AD de Grey (2003) The
foreseeability of real anti-aging medicine: focusing the debate. Exp Gerontol.
38(9):927-34.
- AD de Grey, FC Campbell,
I Dokal, LJ Fairbairn, GJ Graham, CA Jahoda, AC Porterg. (2004) Total deletion
of in vivo telomere elongation capacity: an ambitious but possibly ultimate
cure for all age-related human cancers. Ann N Y Acad Sci. 1019:147-70.
- AD: de Grey, PJ Alvarez,
RO Brady, AM Cuervo, WG Jerome, PL McCarty, RA Nixon, BE Rittmann, JR Sparrow.
Medical bioremediation: prospects for the application of microbial catabolic
diversity to aging and several major age-related diseases. Ageing Res
Rev. 315-38.
- AD de Grey (2005) Whole-body
interdiction of lengthening of telomeres: a proposal for cancer prevention.Front
Biosci. 10:2420-9.
Chronic Fatigue Syndrome
- Keiji Fukada, Stephen
E. Straus, Ian Hickie, Michael C. Sharpe, James C. Dobbins, Anthony Komaroff
(1994) The chronic fatigue syndrome: a comprehensive approach to its definition
and study. Annals of Internal Medicine 121 (12): 953 - 959
- A. Wilson, I. Hickie
A.Lloyd, D. Hadzi-Pavlovic, C. Broughton, J. Dwyer, D. Wakefield (1994) Longitudinal
study of outcome of chronic fatigue syndrome. B.M.J. 308: 756 - 759
- Kathy Y. Fulcher, Peter
D. White. (1997) Randomized controlled trial of graded exercise in patients
with the chronic fatigue syndrome. B.M.J. 314: 1647 - 1652
- J.H.Park, K.J. Neirmann,
N. Olsen (2000) Evidence for metabolic abnormalities in the muscles of
patients with fibromyalgia. Curr. Rheumatol. Rep. 2(2): 131 - 140
- Simon Wesseley, Matthew
Hotopf, Michael Sharpe (1999) Chronic fatigue and its syndromes. OUP
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